Midwives Revision

IMCI · Age: 2 months - 5 years

Severe Complicated Measles

Classification for a child with measles now (or within last 3 months) who has any general danger sign OR clouding of the cornea OR deep/extensive mouth ulcers. Requires urgent referral and specific pre-referral treatments.

View images for Severe Complicated Measles (Google Images, opens in a new tab)
On this page

Care priority and warning signs

Care priority

Refer URGENTLY

Red flags

  • Any general danger sign
  • Clouding of cornea
  • Deep or extensive mouth ulcers
  • Signs of pneumonia (chest indrawing, fast breathing)
  • Stridor
  • Severe malnutrition

Assessment

  • Ask: Does the child have fever?
  • Ask: Has the child had measles within the last 3 months? (Look for generalized rash PLUS one of: cough, runny nose, red eyes).
  • If Yes to Measles:
  • Check for General Danger Signs (Any ONE: Unable to drink/breastfeed, Vomits everything, Had convulsions, Lethargic/unconscious, Convulsing now).
  • Look: Look for clouding of the cornea.
  • Look: Look for deep or extensive mouth ulcers.

Classification

  • Measles now or within last 3 months AND (Any general danger sign OR Clouding of cornea OR Deep/extensive mouth ulcers) -> SEVERE COMPLICATED MEASLES

Key features

  • History of measles (rash + cough/runny nose/red eyes) within last 3 months.
  • Presence of ANY General Danger Sign OR Clouding of Cornea OR Deep/extensive mouth ulcers.
  • Clouding of cornea indicates severe Vitamin A deficiency and risk of blindness.
  • Deep mouth ulcers impair feeding and increase risk of secondary infection/dehydration.
  • Requires Vitamin A, pre-referral antibiotic, and urgent referral.

Management

Non-pharmacological management

  • Quickly complete assessment.
  • Keep child warm.
  • Provide supportive care for breathing/airway if needed.

Pharmacological treatment

  • Give Vitamin A treatment dose TODAY (Day 1). Dose: Age 6-11 months: 100,000 IU (Blue capsule). Age 12 months - 5 years: 200,000 IU (Red/Yellow capsule). (Note: Give 2nd dose on Day 2, 3rd dose after 2 weeks if eye signs present - managed at referral).
  • Give first dose of appropriate IM antibiotic (e.g., Ampicillin + Gentamicin or Ceftriaxone - see page 12 for doses).
  • If clouding of cornea or pus draining from eye: Apply Tetracycline eye ointment (1%) into both eyes.
  • Treat to prevent low blood sugar (as per page 12).
  • Give other necessary pre-referral treatments (e.g., rectal diazepam, antimalarial if co-existing severe classification).

Pre-referral treatment

  • Vitamin A Day 1 dose.
  • First dose IM antibiotic.
  • Tetracycline eye ointment if eye signs.
  • Treat for low blood sugar.
  • Other essential pre-referral treatments.

Follow-up

  • To be managed at referral hospital facility.

Counselling points

  • Explain that measles has caused serious complications requiring hospital care.
  • Explain treatments given (Vit A, antibiotic, eye ointment).
  • Advise on keeping child warm and continuing fluids/breastfeeding if possible during transport.
  • Write a detailed referral note mentioning measles, complications found, and all treatments given.

Differential diagnosis

  • Measles with Eye/Mouth complications (less severe)
  • Uncomplicated Measles
  • Other viral exanthems (e.g., Rubella, Dengue, Enterovirus)
  • Kawasaki disease
  • Drug reaction
  • Severe Vitamin A deficiency (corneal signs)
  • Herpetic stomatitis (mouth ulcers)

Complications

  • Blindness (from corneal ulceration/scarring)
  • Severe Pneumonia
  • Encephalitis
  • Severe Diarrhoea and Dehydration
  • Severe Stomatitis leading to poor intake/malnutrition
  • Otitis Media, Mastoiditis
  • Sepsis
  • Subacute Sclerosing Panencephalitis (SSPE - late complication)
  • Death

Prevention

  • Measles vaccination (2 doses as per national schedule).
  • Vitamin A supplementation (routine).
  • Good nutrition.
  • Prompt treatment of uncomplicated measles.
  • Isolation of cases to prevent spread.

References

IMCI Chart Booklet - Page 4, Pages 1, 12, 18 (eye ointment), 20 (Vit A)

For learning and professional reference. Use current local guidance and clinical judgement.

Browse imci entries

Want notes in PDF? Join our classes!!

Send us a message on WhatsApp
0726113908

Scroll to Top