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Obstetrics

Antepartum Haemorrhage (APH) - Abruptio Placentae & Placenta Praevia

Vaginal bleeding occurring after 28 weeks of gestation but before the onset of the second stage of labour. Main causes are Placenta Praevia and Abruptio Placentae.

Also known as: APH, Bleeding in Late Pregnancy

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Referral and warning signs

When to refer

Urgent Referral/Transfer to Hospital (H/RR) for ALL APH cases. Ensure facility capable of blood transfusion and emergency C/S.

Red flags

  • Heavy vaginal bleeding
  • Signs of shock
  • Severe abdominal pain / Tense uterus
  • Fetal distress / Absent FHR
  • Signs of DIC

Signs and symptoms

  • Placenta Praevia: Painless, bright red vaginal bleeding. Often recurrent. Uterus soft, non-tender. FHR usually present. Malpresentation common.
  • Abruptio Placentae: Vaginal bleeding (often dark, may be concealed). Abdominal pain (constant, severe). Uterus tender, firm, 'woody'. Fetal distress/absent FHR common. Maternal shock may exceed visible loss.
  • Local Causes: Lighter bleeding, often post-coital. Identified on speculum.

Risk factors

  • Praevia: Previous C/S, previous praevia, multiparity, AMA, multiple gestation, smoking.
  • Abruption: Hypertension/PET, previous abruption, trauma, smoking, cocaine, PROM, multiple gestation, polyhydramnios.

Diagnosis

Clinical assessment

History (bleeding onset, amount, colour, pain, trauma). Abdo exam (tone, tenderness, SFH, FHR). Speculum exam (gentle) to rule out local causes. AVOID Digital Vaginal Exam until Praevia excluded by ultrasound.

Investigations

  • Ultrasound Scan: Essential to locate placenta (diagnose/exclude Praevia). May show retroplacental clot (Abruption).
  • FBC (anaemia).
  • Blood Group & Cross-match.
  • Coagulation Screen (esp. if Abruption).
  • Cardiotocography (CTG - assess fetal well-being).

Diagnostic criteria

Clinical presentation (painful vs painless bleed, uterine tone) + Ultrasound (placental location).

Management

Non-pharmacological management

  • Immediate Assessment & Resuscitation (ABC).
  • Establish large-bore IV access (x2).
  • Oxygen.
  • Continuous maternal/fetal monitoring.
  • Hospital Admission for ALL APH.
  • Bed rest.
  • Decision on delivery mode/timing.

Pharmacological treatment

  • IV Fluids (Crystalloids).
  • Blood Transfusion (PRBCs/WB).
  • FFP/Cryo/Platelets (if DIC).
  • Antenatal Corticosteroids (<34 weeks if delivery not imminent).
  • Anti-D Immunoglobulin (Rh-negative).
  • Tocolysis CONTRAINDICATED in significant APH.
  • Management by Cause:
  • - Praevia: Minor bleed/preterm -> Conservative in hospital, steroids <34w, elective C/S 36-37w. Major bleed/labour/term -> Emergency C/S.
  • - Abruption: Fetal distress/Maternal compromise/Term -> Urgent Delivery (usually C/S). Fetus dead/Preterm/Stable -> May consider IOL with close monitoring.

Monitoring

Maternal vitals, blood loss, uterine tone. FHR (CTG). Serial FBC, coagulation.

Complications

  • Maternal: Shock, Anaemia, DIC, AKI, Sheehan's, PPH, Hysterectomy, Death.
  • Fetal/Neonatal: Distress/hypoxia, Stillbirth/Death, Prematurity, IUGR, Anaemia.

Prevention

  • Manage risk factors (hypertension, smoking).
  • Avoid trauma.
  • Manage multiple pregnancies appropriately.

Patient education

  • Explanation of cause.
  • Need for admission/monitoring.
  • Potential risks.
  • Possible need for transfusion/urgent delivery (likely C/S).
  • Report further bleeding/pain immediately.

Uganda-specific notes

Major cause of mortality. Access to ultrasound, blood, emergency C/S critical but often delayed. Clinical differentiation key if no ultrasound. AVOID VE if Praevia suspected.

References

  • Uganda Clinical Guidelines (UCG) 2023

    Chapter 16, Section 16.3.6

For learning and professional reference. Use current local guidance and clinical judgement.

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